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In a multicenter study of occupational HIV exposures, 38% of source patients had genotype mutations associated with resistance to antiretroviral drugs. Recent antiretroviral treatment history was highly associated with resistance.
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It appears safe to conclude that patients with mild-to-moderate angina can be safely managed with continued medical therapy, but percutaneous coronary intervention is certainly indicated and appropriate if anginal symptoms are not controlled by maximum, aggressive medical management.
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Sleep and headache have a long and complex relationship. Morning (or awakening) headache has been linked to sleep disorders, especially obstructive sleep apnea syndrome, but this association is controversial.
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There is an association between long-distance air flights and venous thromboembolism, but the role of traditional risk factors and prophylactic measures requires more study.
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A small subset of patients with evidence of pericardial constriction, perhaps 1 in 6, experience spontaneous resolution without surgical intervention.
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The risk of new AF or HF in subjects older than 65 with echocardiographic evidence of abnormal relaxation increased linearly with the degree of LA enlargement.
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Kahn and colleagues preformed a randomized trial of CPB vs off-pump coronary artery surgery in 104 patients with multivessel disease; Cavendish and associates report on 5 cases in which the Symmetry Bypass Connector was used, who developed acute coronary syndromes 2-5 months after surgery.
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In a collective effort from the tumor registries of 4 academic centers, Huh and colleagues accessioned cases of uterine papillary serous carcinoma (UPSC), which, following comprehensive surgical staging, were identified with disease limited to the uterine corpussurgical stage I.